THYROTROPIN RELEASING HORMONE, [PRO3-3, 4-3H] - Names and Identifiers
THYROTROPIN RELEASING HORMONE, [PRO3-3, 4-3H] - Physico-chemical Properties
THYROTROPIN RELEASING HORMONE, [PRO3-3, 4-3H] - Introduction
THYROTROPIN RELEASING HORMONE [PRO 3,4-3H] is an isotope-labeled compound of thyroid HORMONE RELEASING HORMONE (TRH). This is done by labeling TRH with tritium (3H) on methylated histidine residues. TRH is a peptide hormone secreted by the hypothalamus that regulates the secretion of thyroid hormones by stimulating the release of thyrotropin (TSH) from the anterior pituitary gland.
The main use of thyropin RELEASING HORMONE [PRO 3,4-3H] is as a radioactive tracer in laboratory research. It can be used to study the transport, metabolism and mechanism of TRH in vivo, as well as disease models related to thyroid hormone secretion and regulation.
The method of preparing thyropin RELEASING HORMONE [PRO 3,4-3H] generally involves chemical synthesis and radioisotope labeling of TRH. Chemical synthesis of TRH requires synthetic organic chemistry techniques and appropriate reactions to introduce methylated histidine residues. A reagent labeled with tritium (3H) is then used in the synthesis of TRH to introduce a radioisotope into the compound.
When using thyropin RELEASING HORMONE [PRO 3,4-3H], you need to follow appropriate radiation safety measures, including wearing personal protective equipment, correct handling and storage methods, to avoid radiation exposure and contamination. In addition, depending on the needs of specific experiments, it may be necessary to obtain a suitable permit or license to use radioactive materials.
Last Update:2024-04-09 15:17:46